We are excited to announce that Natasha Rajah from McGill university will be giving a virtual talk on May 6th, 3:30pm EST. Dr. Rajah is a professor in the Department of Psychiatry at McGill University and the Director of the Brain Imaging Centre at the Douglas Research Centre. Broadly speaking, Dr. Rajah’s research employs a lifespan approach to studying cognitive aging processes through behavioral and neuroimaging techniques. On May 6th, Dr. Rajah will present her research examining the effect of age, sex and gender on the neurobiology of episodic memory. To register for the event, please click HERE. Abstract
Our ability to encode, store and retrieve past experiences in rich contextual details declines with age and can be an early sign of Alzheimer’s disease (AD). Rajah will present work from the Montreal Adult Lifespan study that shows episodic memory decline and associated brain changes arise by early midlife (40-59 years old), and middle-aged adults with known risk factors for AD and/or a family history of AD show differences in memory-related brain function compared to those without. This work highlights how midlife is a critical period in adult development when the early signs of pathological aging may first emerge. Midlife is also the time when most women experience menopause, which is associated with decreased levels of endogenous estrogen 17b-estradiol (E2). E2 receptors are densely localized in brain regions critical for memory function. Given that two-thirds of older adults with Alzheimer’s disease are women, it’s important to know whether women's neurocognitive experiences during menopause may help identify sex-specific early markers of pathological aging, which can be used to identify women at risk and provide early access to care. She will close her talk by presenting preliminary findings from this project
10 Comments
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